Utilizing Pharmacogenomics to Reduce Adverse Drug Events
نویسندگان
چکیده
منابع مشابه
Pharmacogenomics and reducing the frequency of adverse drug events.
Drug toxicity and adverse drug events Pharmacogenomics, as applied to medical practice, offers the promise of reduction in adverse drug events (ADEs), enhanced drug efficacy and selection of patients able to respond to specific agents. This editorial will focus on the history and evolving role of pharmacogenetics and pharmacogenomics as it moves from the basic research laboratory into clinical ...
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Adverse drug reactions are a common and important complication of drug therapy in children. Over the past decade it has become increasingly apparent that genetically controlled variations in drug disposition and response are important determinants of adverse events for many important adverse events associated with drug therapy in children. While this research has been difficult to conduct over ...
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Identification of reliable markers to predict drug-related adverse events (DRAEs) is an important goal of the pharmaceutical industry and others within the healthcare community. We have used genetic polymorphisms, including the most frequent source of variation (single nucleotide polymorphisms, SNPs) in the human genome, in pharmacogenetic approaches designed to predict DRAEs. Three studies exe...
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Pharmacogenetics (PGx) - the study of DNA variation in the human genome and the way this impacts the efficacy and safety of medicines - is becoming an increasingly important research tool as physicians, patients, regulatory authorities and payers look for innovative ways to improve the risk:benefit ratio of medicines. While scientific knowledge about PGx is rapidly increasing, implementation of...
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Objective: To increase cancer patients safety in our Day Oncology Care Unit (DOCU). Methods: We conducted a retrospective review of records to determine the most frequent causes of Adverse Drugs Events (ADEs) and the time it took to detect and treat them. We then provided nursing education to instruct oncology nurses on how to address and prevent ADEs. Results: After the implementation of this ...
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ژورنال
عنوان ژورنال: American Journal of Biomedical Science & Research
سال: 2020
ISSN: 2642-1747
DOI: 10.34297/ajbsr.2020.11.001638